Embryology & Implantation Research

Identifying the health of the embryo through genetic or non-invasive methods to enable selection and transfer of embryos with the greatest implantation potential

Identifying a Good Embryo

Identifying a Good Embryo

From a successful IVF cycle, a female will produce one to several good-quality embryos for transfer. However, choosing which of these embryos will have the best chance of growing in the uterus is a difficult task that has, up to now, largely relied on how the embryo looks. We are using new, advanced technologies to identify factors that are released by embryo in culture media which are indicative of good implantation potential. Using normally discarded biological material that is left over from the IVF procedure to identify these factors, we hope to advance our ability to choose the embryo with the greatest potential to establish a healthy pregnancy.

Improving Receptivity of the Uterus

Uterine receptivity plays a major role in embryo implantation. Without a healthy endometrium to attach to, transferred embryos have a lower chance of initiating a pregnancy. We are currently working on therapies with great promise to improve the growth and receptivity of the endometrial cells that line the uterus. These studies are taking advantage of cells that are normally discarded after routine sonohysterograms or endometrial scratching procedures, and studying their growth in a dish under different conditions. We hope that establishing methods for optimally supporting the health of these cells, will lead to new therapies to improve the quality of the endometrium for embryo implantation.

Improving Receptivity of the Uterus