Photo of Valeriy Kuznyetsov

Valeriy Kuznyetsov, PhD

Director, Preimplantation Genetics Research

Valeriy earned his Doctor of Philosophy degree in Biology at the St. Petersburg Research Institute for Animal Genetics and Breeding in Russia, where he studied cytogenetic mechanisms that regulate meiotic and ameiotic parthenogenesis of animal oocytes, and how these mechanisms impact on developmental competence of parthenogenetic embryos after chemical and electrical activation. In his ensuing postdoctoral studies, he conducted research in the field of cloning of animal embryos by nuclear transfer, conversion of interphase nuclei into metaphase chromosomes from single human blastomeres for PGD of chromosomal rearrangements, studied cytogenetic mechanisms leading to duplication of the human sperm genome and  haploidization of human somatic cells, conducted research in development of method of human spermatozoa vitrification without permeable cryoprotectants, production and characterization of human embryonic stem cells (hESC) lines. Valeriy joined the CReATe team in October 2010 as Director of Preimplantation Genetics Program, and established team and Preimplantation Genetic Diagnostic (PGD) and Preimplantation Genetic Screening (PGS) programs using first in IVF-clinics of Canada array comparative genomic hybridization (array-CGH) technique and Next-Generation Sequencing (NGS) technology to investigate chromosomal abnormalities in human preimplantation embryos in ART. He is currently working on the impact of embryo mosaicism on PGS, examining the potential for less- and non-invasive PGD and PGS to test IVF embryos for chromosomal abnormalities and genetic diseases, collaborates on multiple clinic research projects in PGD and PGS, embryology and andrology, and coordinates research training in embryology and PGS at CReATe.